A significant fall in BP during dialysis, so-called intradialytic hypotension (IDH), is an important clinical problem. IDH is common, occurring in 15%–20% of treatments. 1. IDH is often associated with distressing symptoms such as lightheadedness, weakness, muscle cramps, and nausea and vomiting.
What does Intradialytic mean in medical terms?
Medical Definition of intradialytic: occurring or carried out during hemodialysis intradialytic hypotension.
What is the full form of IDH?
The Full form of IDH is Intradialytic Hypotension.
How do you test for IDH mutations?
The IDH1 Mutation Testing assay utilizes PCR amplification and dye termination sequencing of the 5-prime portion of exon 4 of the IDH1 gene using specific PCR primers that cover codons 96-138 of the IDH1 gene.
What does Interdialytic mean?
(int″ĕr-dī″ă-lit′ik) [ inter- + dialytic] Pert. to the interval between treatments with hemodialysis or peritoneal dialysis.
What complication occurs if blood is exposed to high dialysate temperature?
Conversely, higher dialysate temperature resulting in higher blood temperature decreases the peripheral resistance, leading to increased toxin removal, but may cause IDH episodes partly due to vasodilation.
What are complications of dialysis?
- Low blood pressure (hypotension). A drop in blood pressure is a common side effect of hemodialysis.
- Muscle cramps. Although the cause is not clear, muscle cramps during hemodialysis are common.
- Sleep problems.
- Bone diseases.
- High blood pressure (hypertension).
- Fluid overload.
What is IDH mutation?
Mutations in the genes encoding the cytoplasmic and mitochondrial forms of isocitrate dehydrogenase (IDH1 and IDH2, respectively; collectively referred to as IDH) are frequently detected in cancers of various origins, including but not limited to acute myeloid leukaemia (20%), cholangiocarcinoma (20%), chondrosarcoma (
What does IDH stand for in SAP?
IDH is nothing but International Data Harmonization.
What does ight mean?
IGHT is shorthand used in texting and online messaging that means Alright.
What is an IDH test?
Testing for IDH mutations may be useful for diagnosis and prognosis in glioma, and for risk stratification in AML. This test detects mutations in exons 4 of the IDH1 and IDH2 genes, which includes codons 132 (IDH1) and 140 & 172 (IDH2).
What is IDH sequencing?
IDH analysis of gliomas is a novel method of classification and an independent prognostic marker. We compared antibody and sequencing methods for the detection of IDH mutations. Method: 88 samples from 74 patients were identified. For immunohistochemistry: sections were stained with anti-IDH1R132H antibody.
What does IDH wild type mean?
IDH ‘wild’ type status – This occurs in about 90% of GBM brain tumours and usually indicates that the tumour formed as glioblastoma since the very beginning (primary GBM) and carries a worse prognosis than those classified as being IDH mutant.